MEN1, MEN4, and Carney Complex: Pathology and Molecular Genetics
نویسندگان
چکیده
منابع مشابه
MEN1, MEN4, and Carney Complex: Pathology and Molecular Genetics.
Pituitary adenomas are a common feature of a subset of endocrine neoplasia syndromes, which have otherwise highly variable disease manifestations. We provide here a review of the clinical features and human molecular genetics of multiple endocrine neoplasia (MEN) type 1 and 4 (MEN1 and MEN4, respectively) and Carney complex (CNC). MEN1, MEN4, and CNC are hereditary autosomal dominant syndromes ...
متن کاملPneumoviruses: Molecular Genetics and Reverse Genetics
Pneumoviruses are responsible for significant respiratory disease in their hosts and represent a major problemfor human and animal health. Pneumoviruses are members of the family Paramyxoviridae, subfamilyPneumovirinae and the virus particles consist of a negative-sense, nonsegmented RNA genome within a helical nucleocapsid structure enveloped in a lipid membrane derived from the ho...
متن کاملMultiple endocrine neoplasia type 1 (MEN1) and type 4 (MEN4)
Multiple endocrine neoplasia (MEN) is characterized by the occurrence of tumors involving two or more endocrine glands within a single patient. Four major forms of MEN, which are autosomal dominant disorders, are recognized and referred to as: MEN type 1 (MEN1), due to menin mutations; MEN2 (previously MEN2A) due to mutations of a tyrosine kinase receptor encoded by the rearranged during transf...
متن کاملbreast cancer: genetics, risk factors, molecular pathology and treatment
breast cancer within incident of one million new cases each year has become one of the most common malignancies and leading cause of death among females. this disease is comprised of about 18% of women cancers. the availability of early detection and improved treatments may decrease the mortality rates which reflected in the united states and many other western countries. breast cancer in over ...
متن کاملMolecular Genetics and Epidemiology of Vitiligo
Background: Vitiligo is an acquired, idiopathic, and common depigmentation disorder of the skin that affects people of all ages and both sexes equally in the worldwide. Although etiology of the disease is unknown, there are theories such as environment and genetic factors. Methods: In this article, we collected and summarized the appropriate manuscripts regarding the epidemiology and gene...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Neuroendocrinology
سال: 2015
ISSN: 0028-3835,1423-0194
DOI: 10.1159/000371819